The Patriots host the Detroit Lions in a week 5 matchup that features the red throwback jerseys for the first time in 10 years. The Lions (1-3) are looking to prove skeptics wrong that their high-powered offense can carry their struggling defense.

Meanwhile, the Patriots are hoping to avoid a third straight loss with rookie quarterback Bailey Zappe making his first NFL start.

Without further ado, let’s get into the key matchups that could decide the fate of this week’s game for the Patriots.